sorrow

noun

1
something that causes great unhappiness
her death was a great grief to John
2
an emotion of great sadness associated with loss or bereavement
he tried to express his sorrow at her loss
3
sadness associated with some wrong done or some disappointment
he drank to drown his sorrows
he wrote a note expressing his regret
4
the state of being sad
she tired of his perpetual sadness

Also useful for “sorrow”:Unscrambler— Rearrange the letters in “sorrow”