irritate

verb

1. 1

   excite to an abnormal condition, or chafe or inflame

   Aspirin irritates my stomach

2. 2

   excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus

   irritate the glands of a leaf

3. 3

   cause annoyance in; disturb, especially by minor irritations

   Mosquitoes buzzing in my ear really bothers me

   It irritates me that she never closes the door after she leaves